Many women navigating midlife and menopause seek ways to support their energy levels and cognitive function. Among the various botanical options, Ginkgo biloba and Panax ginseng are frequently discussed for these potential benefits. Both have a history of traditional use and have been the subject of modern research.
This article will explore the current understanding of Ginkgo biloba and Panax ginseng, examining what the available evidence suggests about their individual and combined effects on energy and cognition. We will also highlight important considerations for women considering these supplements.
Understanding Ginkgo Biloba
Ginkgo biloba is derived from one of the oldest living tree species. Extracts from its leaves are commonly used in supplements. It is often recognized for its potential role as a cognitive enhancer [1]. Research has explored various aspects of ginkgo’s effects, particularly concerning brain function.
Some studies have investigated Ginkgo biloba’s impact on cognitive performance. For instance, a study looking at single-dose effects found no statistically significant difference in driving performance with Ginkgo biloba or Panax ginseng, each given on its own [2]. Another randomized trial explored how Ginkgo biloba and Panax ginseng, each given separately, affected cognition, with ginkgo improving aspects of executive functioning in females but not in males [3].
It’s worth noting that Ginkgo biloba is sometimes discussed in the context of brain health and optimal brain functions [4]. Its mechanisms are thought to involve various pathways that may support neurological processes.
Understanding Panax Ginseng
Panax ginseng is a root known for its adaptogenic properties, meaning it may help the body adapt to stress. Like Ginkgo biloba, Panax ginseng is also considered a potential cognitive enhancer [1]. It has been a subject of interest for its potential to support both physical and mental well-being.
Research has delved into ginseng’s effects on cognition. A randomized trial investigated Panax ginseng’s influence on cognition and found that ginseng had no effect on cognition [3]. Furthermore, a study examining single-dose effects reported no statistically significant difference in driving performance with Panax ginseng or with Ginkgo biloba compared with placebo [2].
Ginseng is often considered for its potential to support overall vitality, which can indirectly contribute to feelings of energy and mental clarity during midlife. Its potential role in supporting optimal brain functions is also a topic of ongoing discussion [4].
Ginkgo Biloba and Panax Ginseng: Combined Effects
While both Ginkgo biloba and Panax ginseng have been studied individually, their combination is also a common area of interest. Some products combine these two botanicals, leading to questions about their synergistic or additive effects. A systematic review examined research investigating the physiological and psychological effects of combining Ginkgo biloba and Panax ginseng into a single treatment in humans [5]. This review highlighted implications for research design and analysis when studying such combinations.
A randomized trial specifically investigated the effects of both individual Ginkgo biloba and Panax ginseng on cognition. This study found that ginkgo improved aspects of executive functioning in females but not in males, while ginseng had no effect on cognition [3]. Another study looking at single-dose effects observed no statistically significant difference in driving performance with Ginkgo biloba or Panax ginseng, each given on its own [2].
The rationale for combining these two often stems from the idea that they might complement each other’s potential benefits, addressing different aspects of cognitive function or energy support. However, understanding the precise interactions and optimal dosages in combination requires careful research.
Which is ‘Better’ for Midlife Energy and Cognition?
When comparing Ginkgo biloba and Panax ginseng for energy and cognition in midlife, it’s important to recognize that ‘better’ can be subjective and depend on individual responses and specific needs. Both are considered potential cognitive enhancers [1] and have been explored for their effects on brain function.
The evidence for both individual and combined use suggests moderate support for their roles in cognitive processes. For example, one small crossover trial found ginkgo improved aspects of executive functioning in females but not in males while ginseng had no effect on cognition, and a single-dose driving simulator study found no significant difference for either herb [3][2]. There are also discussions about similarities and differences between Ginkgo biloba and Panax notoginseng (a related species) in the context of cerebrovascular health [6], which indirectly relates to cognitive support.
Currently, there isn’t a definitive scientific consensus stating one is unequivocally ‘better’ than the other for all individuals or all aspects of energy and cognition. The choice may depend on whether an individual seeks specific cognitive support, general vitality, or a combination of benefits. Consulting with a healthcare provider can help tailor decisions based on personal health profiles and goals.
References
- Nootropic Herbs, Shrubs, and Trees as Potential Cognitive Enhancers. Plants (Basel, Switzerland), 2023
- Effect of single-dose Ginkgo biloba and Panax ginseng on driving performance. Clinical toxicology (Philadelphia, Pa.), 2015
- Ginseng and Ginkgo Biloba Effects on Cognition as Modulated by Cardiovascular Reactivity: A Randomised Trial. PloS one, 2016
- A Mini-Review on Unlocking Cognitive Enhancement: An Innovative Strategy for Optimal Brain Functions. Central nervous system agents in medicinal chemistry, 2025
- A systematic review of research investigating the physiological and psychological effects of combining Ginkgo biloba and Panax ginseng into a single treatment in humans: Implications for research design and analysis. Brain and behavior, 2019
- [Similarities and differences between Ginkgo biloba and Panax notoginseng in treatment of ischemic cerebrovascular disease]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2020
These statements have not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure, or prevent any disease. Content is for informational purposes only and is not medical advice; consult a qualified healthcare provider before starting any supplement. As an Amazon Associate we earn from qualifying purchases.
